The Baliga Lab develops predictive models to explain, predict and manipulate complex biological behaviors in order to catalyze strategies for personalized medicine, formulating effective therapies for tuberculosis, and crafting solutions for a sustainable environment. Interaction with the environment is central to how information within our DNA is decoded into observable phenotypes. Dr. Baliga and his laboratory are using a multidisciplinary systems approach to understand this process. Once delineated, the engineering principles governing assembly of biological systems will help unlock potentials within diverse organisms, and enable spectacular solutions for problems in environment, global health and medicine.