The Straehla Lab, located at Seattle Children’s Research Institute, focuses on accelerating the translation of drug delivery technologies for cancer therapy, with a special emphasis on using nanomedicines in cancers. Led by Dr. Joelle Straehla, a pediatric oncologist specializing in brain and spinal cord tumors, the lab operates at the intersection of nanotechnology and cancer biology. The lab’s primary objectives include 1) Designing and synthesizing new nanoparticle-based therapeutics 2) Identifying biologic regulators of nanoparticle drug delivery 3) Improving the delivery of therapeutic agents across challenging tissue barriers and 4) Developing strategies to selectively remodel the tumor microenvironment. Read More
As a graduate student in Richard James’s lab at the Center for Immunity and Immunotherapies at Seattle Children's Research Institute, Rene studies how to experimentally reprogram human B cells to long-lived antibody secretion cells by developing a mathematical model of cell differentiation. This research will help design new protein deficiency therapies as a life-long treatment and antibody vaccine. Rene holds a B.S. in Clinical Laboratory Science and Medical Biotechnology from National Taiwan University. Read More