High glucose levels could impair ferroelectricity in body's connective tissues

High sugar levels in the body come at a cost to health. New research suggests that more sugar in the body could damage the elastic proteins that help us breathe and pump blood. The findings could have health implications for diabetics, who have high blood-glucose levels.

Researchers at the University of Washington and Boston University have discovered that a certain type of protein found in organs that repeatedly stretch and retract such as the heart and lungs is the source for a favorable electrical property that could help build and support healthy connective tissues. Read More

New device could cut costs on household products, pharmaceuticals

New device could cut costs on household products, pharmaceuticals By Michelle Ma Sometimes cost saving comes in nanoscale packages. A new procedure that thickens and thins fluid at the micron level could save consumers and manufacturers money, particularly for soap products that depend on certain molecules to effectively deal with grease and dirt. Researchers at the University of Washington published their findings online April 9 in the Proceedings of the National Academy of Sciences. Read the back of most shampoos and dishwashing detergents and you'll find the word "surfactant" in the list of active ingredients. Read More

Rules devised for building ideal protein molecules from scratch

By Leila Gray, UW Health Sciences/UW Medicine
November 29, 2012

By following certain rules, scientists can prepare architectural plans for building ideal protein molecules not found in the real world. Based on these computer renditions, previously non-existent proteins can be produced from scratch in the lab. The principles to make this happen appear this month in Nature magazine.

The lead authors are Nobuyasu Koga and Rie Tatsumi-Koga, a husband-and-wife scientific team in David Baker's lab at the UW Protein Design Institute. Read More

Sticky paper offers cheap, easy solution for paper-based diagnostics

Global health researchers, including MolES faculty member Dan Ratner, are working on cheap systems like a home-based pregnancy test that might work for malaria, diabetes or other diseases. A new chemical technique makes medically interesting molecules stick to regular paper "” a possible route to building such paper-based diagnostics from paper you could buy at an office-supply store.