Break it up: Polymer derived from material in shrimp's shells could deliver anti-cancer drugs to tumor sites

Images of mouse mammary cancer cells under a microscope.
A University of Washington team led by Miqin Zhang, a MolES faculty member and professor of materials science and engineering, has developed a nanoparticle-based drug delivery system that can ferry a potent anti-cancer drug through the bloodstream safely. Their nanoparticle is derived from chitin, a natural and organic polymer that, among other things, makes up the outer shells of shrimp.

MolES faculty receive NSF EAGER award to develop new SARS-CoV-2 antibody test

James Carothers and Jesse Zalatan
James Carothers, Dan Evans Career Development Associate Professor of Chemical Engineering, and Jesse Zalatan, Assistant Professor of Chemistry, have been awarded a National Science Foundation EAGER grant to develop a new type of SARS-Cov-2 antibody test. Carothers and Zalatan will receive $300,000 over a one-year period from funds made available through the Coronavirus Aid, Relief, and Economic Security (CARES) Act.

Developing rapid COVID-19 tests for the home and clinic

SARS-CoV-2 blue and yellow
At the onset of the #COVID-19 pandemic, MolES faculty member Paul Yager, a UW professor of bioengineering, knew a rapid and accurate test would be needed to screen patients for the new coronavirus. He immediately set to work adapting his point-of-care testing research to developing an at-home test for the new virus. Read more about how the Yager lab is developing easy, fast and accurate COVID-19 tests to be used at home and in the clinic.

Meeting the need for COVID-19 test kits: Pivoting from Seattle Flu Study and developing new rapid tests

UW bioengineering research scientists Enos Kline
MolES faculty member and bioengineering professor Barry Lutz, in partnership with Dr. Matthew Thompson, a UW professor of family medicine and global health, is pioneering at home test kits for the Seattle Coronavirus Assessment Network to respond to the COVID-19 pandemic. Read more about how the Lutz lab is developing new ways to rapidly test for COVID-19.

COVID-19 Research at MolES

In response to the COVID-19 pandemic, MolES faculty have pivoted their research to address the novel coronavirus, SARS-CoV-2. They are leveraging molecular engineering approaches and tools to develop improved diagnostics, targeted treatment strategies, and a better understanding of the virus. We highlight a few of these projects here.

Designing proteins that can sequence DNA

Sinduja Marx has long been interested in developing miniaturized, parallelized and personalized sequencing and diagnostics tools. As a molecular engineering grad student in the labs of physics professor Jens Gundlach, and Institute for Protein Design director David Baker, Marx is designing synthetic biological channels for nanopore DNA sequencing and molecular diagnostics. In this Q&A, Marx talks about her research and advice for prospective grad students.